BDBM546595 US11292781, Compound T80

SMILES C[C@@H]1[C@H]2CCc3c(nc(nc3[C@]2(C)C=C(C#N)C1=O)-c1ccnc2CCCc12)-c1ccccc1F

InChI Key InChIKey=YEPACXFBNRTSCF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 546595   

TargetNuclear receptor ROR-gamma(Human)
Reata Pharmaceuticals

US Patent
LigandPNGBDBM546595(US11292781, Compound T80)
Affinity DataIC50: 82nMAssay Description:The RORγ assay system was purchased from Indigo Biosciences. This nuclear receptor assay utilizes a human cell line that has been engineered to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
US Patent