BDBM546640 US11292781, Compound T123

SMILES CC(C)c1cc(-c2nc(c3CC[C@@H]4[C@@H](C)C(=O)C(=C[C@@]4(C)c3n2)C#N)-c2ccccc2F)c2ccccc2n1

InChI Key InChIKey=OHGGZKZENHUJDV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 546640   

TargetNuclear receptor ROR-gamma(Human)
Reata Pharmaceuticals

US Patent
LigandPNGBDBM546640(US11292781, Compound T123)
Affinity DataIC50: 55nMAssay Description:The RORγ assay system was purchased from Indigo Biosciences. This nuclear receptor assay utilizes a human cell line that has been engineered to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
US Patent