BDBM547775 Methyl (3S)-3-(((5R)-5-oxido-2-(3-phenylazetidin-1-yl)-6,7-dihydrothieno[3,2-d]pyrimidin-4-yl)amino)pyrrolidine-1-carboxylate::US11292799, Example 5

SMILES COC(=O)N1CC[C@@H](C1)Nc1nc(nc2CC[S@@+]([O-])c12)N1CC(C1)c1ccccc1

InChI Key InChIKey=CBWAZCGJQGORMH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 547775   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [538-740](Human)
Union Therapeutics

US Patent
LigandPNGBDBM547775(Methyl (3S)-3-(((5R)-5-oxido-2-(3-phenylazetidin-1...)
Affinity DataIC50: 30nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [5380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
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