BDBM547777 Methyl (3R)-3-(((5R)-2-(3-(4-Fluorophenoxy)azetidin-1-yl)-5-oxido-6,7-dihydrothieno[3,2-d]pyrimidin-4-yl)amino)piperidine-1-carboxylate::US11292799, Example 7

SMILES COC(=O)N1CCC[C@H](C1)Nc1nc(nc2CC[S@@+]([O-])c12)N1CC(C1)Oc1ccc(F)cc1

InChI Key InChIKey=OFFGVIDDSBLDCJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 547777   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [538-740](Human)
Union Therapeutics

US Patent
LigandPNGBDBM547777(Methyl (3R)-3-(((5R)-2-(3-(4-Fluorophenoxy)azetidi...)
Affinity DataIC50: 10nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [5380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
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