BDBM547781 (R)-4-(Bicyclo[1.1.1]pentan-1-ylamino)-2-(3-phenylazetidin-1-yl)-6,7-dihydrothieno[3,2-d]pyrimidine 5-oxide::US11292799, Example 11

SMILES [O-][S@@+]1CCc2nc(nc(NC34CC(C3)C4)c12)N1CC(C1)c1ccccc1

InChI Key InChIKey=DNTFEMDQAREWBU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 547781   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D [538-740](Human)
Union Therapeutics

US Patent
LigandPNGBDBM547781((R)-4-(Bicyclo[1.1.1]pentan-1-ylamino)-2-(3-phenyl...)
Affinity DataIC50: 10nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [5380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
Go to US Patent