BDBM549137 BDBM50556879::Sodium (R)-4-(N-(4-cyclohexylbenzyl)-1-((perfluorophenyl)sulfonyl)azetidine-2-carboxamido)-5-fluoro-2-hydroxybenzoate::US11299480, Example 62

SMILES Oc1cc(N(Cc2ccc(cc2)C2CCCCC2)C(=O)[C@H]2CCN2S(=O)(=O)c2c(F)c(F)c(F)c(F)c2F)c(F)cc1C([O-])=O

InChI Key InChIKey=DSTDCVGDUDNSTO-UHFFFAOYSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 549137   

TargetSignal transducer and activator of transcription 3(Mouse)
University of Hawaii Cancer Center

Curated by ChEMBL
LigandPNGBDBM549137(Sodium (R)-4-(N-(4-cyclohexylbenzyl)-1-((perfluoro...)
Affinity DataIC50: 560nMAssay Description:Inhibition of oligonucleotide [32P]-labelled 5'-AGCITCATTTCCCGTAAATCCCTA probe binding to STAT3 SH2 domain in mouse NIH3T3/v-Src nuclear extract prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Hawaii

US Patent
LigandPNGBDBM549137(Sodium (R)-4-(N-(4-cyclohexylbenzyl)-1-((perfluoro...)
Affinity DataIC50: 562nMAssay Description:Nuclear extract preparations and DNA-binding activity/electrophoretic mobility shift assay (EMSA) were carried out as previously described (Zhang X, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2022
Entry Details
Go to US Patent