BDBM549189 US11299493, Compound 1.14::US11299493, S-14

SMILES CCn1n(-c2cccc(n2)C(C)(C)O)c2nc(Nc3ccc4c(CN(CC4(C)C)C(=O)CO)c3)ncc2c1=O

InChI Key InChIKey=RXLVFKBQEXRTHM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 549189   

TargetWee1-like protein kinase(Human)
Nuvation Bio

US Patent
LigandPNGBDBM549189(US11299493, S-14 | US11299493, Compound 1.14)
Affinity DataIC50: 1nMAssay Description:IC50 values of compounds against WEE1 kinase enzyme were determined by LanthaScreen Terbium Labeled TR-FRET assay. Kinase assays were performed in 1×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent