BDBM549241 US11299493, Compound 1.157::US11299493, S-60

SMILES CC(C)(C)c1cc(ccn1)-n1n(CC=C)c(=O)c2cnc(Nc3ccc4CNCCc4c3)nc12

InChI Key InChIKey=AWXCDDWXUICGGZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 549241   

TargetWee1-like protein kinase(Human)
Nuvation Bio

US Patent
LigandPNGBDBM549241(US11299493, S-60 | US11299493, Compound 1.157)
Affinity DataIC50: 5nMAssay Description:IC50 values of compounds against WEE1 kinase enzyme were determined by LanthaScreen Terbium Labeled TR-FRET assay. Kinase assays were performed in 1×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent