BDBM549242 US11299493, Compound 1.158::US11299493, S-61

SMILES CC(C)(C)c1cc(ccn1)-n1n(CC=C)c(=O)c2cnc(Nc3ccc4CCNCc4c3)nc12

InChI Key InChIKey=GDKOKWYTBGLEPV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 549242   

TargetWee1-like protein kinase(Human)
Nuvation Bio

US Patent
LigandPNGBDBM549242(US11299493, S-61 | US11299493, Compound 1.158)
Affinity DataIC50: 4nMAssay Description:IC50 values of compounds against WEE1 kinase enzyme were determined by LanthaScreen Terbium Labeled TR-FRET assay. Kinase assays were performed in 1×...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2022
Entry Details
US Patent