BDBM54959 3-(2-furyl)-6-m-phenetyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole::6-(3-ethoxyphenyl)-3-(2-furanyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole::6-(3-ethoxyphenyl)-3-(furan-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole::VU0228593-3::cid_662842

SMILES CCOc1cccc(c1)-c1nn2c(nnc2s1)-c1ccco1

InChI Key InChIKey=AKWTVMAIUSIXCS-UHFFFAOYSA-N

Data  4 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 54959   

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM54959(6-(3-ethoxyphenyl)-3-(2-furanyl)-[1,2,4]triazolo[3...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of hexa-His-tagged recombinant human SIRT1 expressed in Escherichia coli BL21(DE3) using AMC-labeled Arg-His-Lys-Lys(ac) as substrate asse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
LigandPNGBDBM54959(6-(3-ethoxyphenyl)-3-(2-furanyl)-[1,2,4]triazolo[3...)
Affinity DataEC50: >3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandPNGBDBM54959(6-(3-ethoxyphenyl)-3-(2-furanyl)-[1,2,4]triazolo[3...)
Affinity DataEC50: >3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
LigandPNGBDBM54959(6-(3-ethoxyphenyl)-3-(2-furanyl)-[1,2,4]triazolo[3...)
Affinity DataEC50: >3.00E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetEnvelope glycoprotein gp160(HIV-1)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM54959(6-(3-ethoxyphenyl)-3-(2-furanyl)-[1,2,4]triazolo[3...)
Affinity DataIC50: 6.71E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetEnvelope glycoprotein gp160(HIV-1)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM54959(6-(3-ethoxyphenyl)-3-(2-furanyl)-[1,2,4]triazolo[3...)
Affinity DataIC50: 6.71E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetEnvelope glycoprotein gp160(HIV-1)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM54959(6-(3-ethoxyphenyl)-3-(2-furanyl)-[1,2,4]triazolo[3...)
Affinity DataIC50: 6.71E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay