BDBM549779 (3R*,4R*)-1-Cyclopropylmethyl-4-{[5-(2,4,6-trifluoro-phenyl)-isoxazole-3- carbonyl]-amino}-piperidine-3-carboxylic acid (1-pyridin-2-yl-cyclopropyl)- amide (enantiomer 1)::US11306078, Example 1.171a

SMILES Fc1cc(F)c(-c2cc(no2)C(=O)N[C@@H]2CCN(CC3CC3)C[C@H]2C(=O)NC2(CC2)c2ccccn2)c(F)c1

InChI Key InChIKey=DTJZXIVLVNYZPK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 549779   

TargetAtypical chemokine receptor 3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM549779((3R*,4R*)-1-Cyclopropylmethyl-4-{[5-(2,4,6-trifluo...)
Affinity DataIC50: 7nMAssay Description:Tango CXCR7-bla U2OS cells are detached from culture dishes with 0.05% trypsin-EDTA and collected in growing medium (McCoy's 5A 90% (v/v), dialyz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent