BDBM550254 2-(2-chloro-4-(2- ((4-(2- fluoropyridin-3- yl)-5- methylthiazol-2- yl)amino)-2- oxoethyl)phenoxy) nicotinamide::US11306081, Example 102

SMILES Cc1sc(NC(=O)Cc2ccc(Oc3ncccc3C(N)=O)c(Cl)c2)nc1-c1cccnc1F

InChI Key InChIKey=HYHPWTKZUZRHTF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550254   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM550254(2-(2-chloro-4-(2- ((4-(2- fluoropyridin-3- yl)-5- ...)
Affinity DataIC50: 12nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
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