BDBM550264 US11306081, Example 112

SMILES CC(C)(O)COc1ccc2sc(NC(=O)Cc3ccc(Oc4ncccc4C(N)=O)c(Cl)c3)nc2c1

InChI Key InChIKey=VDEWYYVWMVGTRD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550264   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM550264(US11306081, Example 112)
Affinity DataIC50: 6nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent