BDBM550275 2-(4-(2-((1-(2,2- difluoroethyl)-6- methoxy-1H-benzo- [d]imidazol-2-yl)- amino)-2-oxoethyl)- 2-fluorophenoxy)- nicotinamide::US11306081, Example 123

SMILES COc1ccc2nc(NC(=O)Cc3ccc(Oc4ncccc4C(N)=O)c(F)c3)n(CC(F)F)c2c1

InChI Key InChIKey=DSAUQYLXJQKSOA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550275   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM550275(2-(4-(2-((1-(2,2- difluoroethyl)-6- methoxy-1H-ben...)
Affinity DataIC50: 18nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
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