BDBM550289 2-(2-fluoro- 4-(2-((7-(1- methyl-1H- pyrazol-5- yl)-[1,2,4]- triazolo[1,5- a]pyridin-2- yl)amino)-2- oxoethyl)- phenoxy) nicotinamide::US11306081, Example 137

SMILES Cn1nccc1-c1ccn2nc(NC(=O)Cc3ccc(Oc4ncccc4C(N)=O)c(F)c3)nc2c1

InChI Key InChIKey=WLYQIEVTXGXUDE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550289   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM550289(2-(2-fluoro- 4-(2-((7-(1- methyl-1H- pyrazol-5- yl...)
Affinity DataIC50: 13nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent