BDBM550313 2-(4-(2-((1- (cyclopropyl- methyl)-4-fluoro- 1H-benzo[d]- imidazol-2-yl)- amino)-2- oxoethyl)-2- fluorophenoxy)- nicotinamide::US11306081, Example 161

SMILES NC(=O)c1cccnc1Oc1ccc(CC(=O)Nc2nc3c(F)cccc3n2CC2CC2)cc1F

InChI Key InChIKey=QRZOOGMNBAFQNM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550313   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM550313(2-(4-(2-((1- (cyclopropyl- methyl)-4-fluoro- 1H-be...)
Affinity DataIC50: 16nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent