BDBM550315 2-(4-(2-((1-(cyclo- propylmethyl)-4- methoxy-1H- benzo[d]imidazol- 2-yl)amino)-2- oxoethyl)-2- fluorophenoxy)- nicotinamide::US11306081, Example 163

SMILES COc1cccc2n(CC3CC3)c(NC(=O)Cc3ccc(Oc4ncccc4C(N)=O)c(F)c3)nc12

InChI Key InChIKey=SLFMWHLMCWZYLM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550315   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM550315(2-(4-(2-((1-(cyclo- propylmethyl)-4- methoxy-1H- b...)
Affinity DataIC50: 16nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
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Date in BDB:
7/31/2022
Entry Details
US Patent