BDBM550321 2-(4-(2-((1-(2,2- difluoroethyl)- 4-fluoro-1H- benzo[d]- imidazol-2-yl)- amino)-2-oxo- ethyl)-2-fluoro- phenoxy)nicotin- amide::US11306081, Example 169

SMILES NC(=O)c1cccnc1Oc1ccc(CC(=O)Nc2nc3c(F)cccc3n2CC(F)F)cc1F

InChI Key InChIKey=HTOGGPPMVUMBCH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550321   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM550321(2-(4-(2-((1-(2,2- difluoroethyl)- 4-fluoro-1H- ben...)
Affinity DataIC50: 13nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
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Date in BDB:
7/31/2022
Entry Details
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