BDBM550326 2-(2-chloro-4- (2-((1-(cyclo- propylmethyl)- 5-fluoro-1H- benzo[d]- imidazol-2-yl)- amino)-2-oxo- ethyl)phenoxy)- nicotinamide::US11306081, Example 174

SMILES NC(=O)c1cccnc1Oc1ccc(CC(=O)Nc2nc3cc(F)ccc3n2CC2CC2)cc1Cl

InChI Key InChIKey=BVAWUHMTBUKGOL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550326   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM550326(2-(2-chloro-4- (2-((1-(cyclo- propylmethyl)- 5-flu...)
Affinity DataIC50: 10nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
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