BDBM550810 8-(2-Methyl-6-(trifluoromethyl)pyridin-4-yl)-7-phenylimidazo[1,2-c]pyrimidin-5-amine::US11312705, Example 17

SMILES Cc1cc(cc(n1)C(F)(F)F)-c1c(nc(N)n2ccnc12)-c1ccccc1

InChI Key InChIKey=MRHNBFYFTSXUGC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 550810   

TargetAdenosine receptor A2a(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM550810(8-(2-Methyl-6-(trifluoromethyl)pyridin-4-yl)-7-phe...)
Affinity DataIC50: 0.75nMAssay Description:CHO-K1/A2aR cells were cultured in DMEM/F12 medium containing 10% fetal bovine serum and 800 μg/ml bleomycin. The cells were digested with the c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent