BDBM550824 8-(2-Cyclopropyl-6-methylpyridin-4-yl)-7-phenyl-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine 30::US11312705, Example 30

SMILES Cc1cc(cc(n1)C1CC1)-c1c(nc(N)n2cnnc12)-c1ccccc1

InChI Key InChIKey=HWPHKAOQDAQSRN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 550824   

TargetAdenosine receptor A2a(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM550824(8-(2-Cyclopropyl-6-methylpyridin-4-yl)-7-phenyl-[1...)
Affinity DataIC50: 0.770nMAssay Description:CHO-K1/A2aR cells were cultured in DMEM/F12 medium containing 10% fetal bovine serum and 800 μg/ml bleomycin. The cells were digested with the c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM550824(8-(2-Cyclopropyl-6-methylpyridin-4-yl)-7-phenyl-[1...)
Affinity DataIC50: 0.770nMAssay Description:CHO-K1/A2aR cells were cultured in DMEM/F12 medium containing 10% fetal bovine serum and 800 μg/ml bleomycin. The cells were digested with the c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM550824(8-(2-Cyclopropyl-6-methylpyridin-4-yl)-7-phenyl-[1...)
Affinity DataIC50: 70.9nMAssay Description:CHO-K1/A2bR cells were cultured in DMEM/F12 medium containing 10% fetal bovine serum and 1 mg/ml G418. The cells were digested with the cell separati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent