BDBM552558 WO2022098970, Example 6

SMILES CC(C)(c1cc(NC(=O)Cc2ccc(cc2)-c2nn(c(N)c2C(N)=O)C2(C)CC2)on1)C(F)(F)F

InChI Key InChIKey=FLDFAQHFTLTSIW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 552558   

LigandPNGBDBM552558(WO2022098970, Example 6)
Affinity DataIC50: 150nMAssay Description:Compounds of formulas I, la to lx, Ila to IIx, and/or Illa to IIIx are screened for their ability to inhibit wildtype, V804M, and G810S mutant RET ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022098970

LigandPNGBDBM552558(WO2022098970, Example 6)
Affinity DataIC50: 150nMAssay Description:Compounds of formulas I, la to lx, Ila to IIx, and/or Illa to IIIx are screened for their ability to inhibit wildtype, V804M, and G810S mutant RET ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022098970

LigandPNGBDBM552558(WO2022098970, Example 6)
Affinity DataIC50: 150nMAssay Description:Compounds of formulas I, la to lx, Ila to IIx, and/or Illa to IIIx are screened for their ability to inhibit wildtype, V804M, and G810S mutant RET ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022098970