BDBM552584 WO2022098970, Example 324

SMILES CC(C)n1nc(c(C(N)=O)c1N)-c1ccc(CC(=O)Nc2cc(no2)-c2ccc(C)cc2F)nc1

InChI Key InChIKey=GYCCWVZGHIXKBN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 552584   

LigandPNGBDBM552584(WO2022098970, Example 324)
Affinity DataIC50: 150nMAssay Description:Compounds of formulas I, la to lx, Ila to IIx, and/or Illa to IIIx are screened for their ability to inhibit wildtype, V804M, and G810S mutant RET ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022098970

LigandPNGBDBM552584(WO2022098970, Example 324)
Affinity DataIC50: 150nMAssay Description:Compounds of formulas I, la to lx, Ila to IIx, and/or Illa to IIIx are screened for their ability to inhibit wildtype, V804M, and G810S mutant RET ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022098970

LigandPNGBDBM552584(WO2022098970, Example 324)
Affinity DataIC50: 150nMAssay Description:Compounds of formulas I, la to lx, Ila to IIx, and/or Illa to IIIx are screened for their ability to inhibit wildtype, V804M, and G810S mutant RET ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022098970