BDBM552648 WO2022101377, Example 47

SMILES Cc1ncc(CNC(=O)[C@@H]2Cc3sc-4c([C@@H](NCc5nnc(C)n-45)c4ccccc4Cl)c3C2)s1

InChI Key InChIKey=FJYNIEYOBQOHQL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552648   

TargetPlatelet-activating factor receptor(Human)
Boehringer Ingelheim International

WIPO
LigandPNGBDBM552648(WO2022101377, Example 47)
Affinity DataIC50: 12nMAssay Description:USING AN ENDPOINT ASSAY HEK293 cells overexpressing human PAFR (produced in-house) are seeded into a Poly-D-Lysine coated 384 well white cell culture...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022101377