BDBM552750 (2S, 4R)-1-((S)-2-(4-cyclopropyl-1H-1,2,3-triazol-1-yl)-3,3-dimethylbutanoyl)-4-hydroxy-N-(1-(trifluoromethyl)cyclopropyl)pyrrolidine-2-carboxamide (Compound 19)::WO2022104345, Compound 19::WO2022104345, Example S18

SMILES CC(C)(C)[C@@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NC1(CC1)C(F)(F)F)n1cc(nn1)C1CC1

InChI Key InChIKey=DEHJSKYQHSFASI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552750   

LigandPNGBDBM552750(WO2022104345, Compound 19 | (2S, 4R)-1-((S)-2-(4-c...)
Affinity DataIC50: 4.99E+3nMAssay Description:The VHL NanoBRET Target Engagement Assay analyzes the apparent affinity of test compounds for VHL in cells by competitive displacement of a VHL NanoB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104345