BDBM552754 (2S, 4R)-1-[(2S)-2-(4-cyclopentyltriazol-1-yl)-3-methyl-butanoyl]-4-hydroxy-N-methyl-pyrrolidine-2-carboxamide (Compound 23) Synthesis was carried out following the scheme given below:::WO2022104345, Compound 23::WO2022104345, Example S22

SMILES CNC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@H](C(C)C)n1cc(nn1)C1CCCC1

InChI Key InChIKey=NKEQFMNXPFWCQA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552754   

LigandPNGBDBM552754(WO2022104345, Compound 23 | (2S, 4R)-1-[(2S)-2-(4-...)
Affinity DataIC50: 3.21E+3nMAssay Description:The VHL NanoBRET Target Engagement Assay analyzes the apparent affinity of test compounds for VHL in cells by competitive displacement of a VHL NanoB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104345