BDBM552759 (2S, 4R)-1-[2-(4-cyclopropyltriazol-1-yl)-3-methyl-but-2-enoyl]-4-hydroxy-N-methyl-pyrrolidine-2-carboxamide (Compound 32)::WO2022104345, Compound 32::WO2022104345, Example S27

SMILES [#6]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6@@H](-[#8])-[#6]-[#7]-1-[#6](=O)-[#6](=[#6](/[#6])-[#6])\n1cc(nn1)-[#6]-1-[#6]-[#6]-1

InChI Key InChIKey=XMVCQUUAOIBMJQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552759   

LigandPNGBDBM552759(WO2022104345, Compound 32 | (2S, 4R)-1-[2-(4-cyclo...)
Affinity DataIC50: 4.75E+3nMAssay Description:The VHL NanoBRET Target Engagement Assay analyzes the apparent affinity of test compounds for VHL in cells by competitive displacement of a VHL NanoB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104345