BDBM552766 (2S,4R)-4-hydroxy-N-methyl-1-((S)-3-methyl-2-(4-phenyl-1H-1,2,3-triazol-1-yl)butanoyl)pyrrolidine-2-carboxamide (Compound 43) Synthesis was carried out following the scheme given below:::WO2022104345, Compound 43::WO2022104345, Example S34

SMILES CNC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@H](C(C)C)n1cc(nn1)-c1ccccc1

InChI Key InChIKey=SUDMCHPHEYNCPS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552766   

LigandPNGBDBM552766(WO2022104345, Compound 43 | (2S,4R)-4-hydroxy-N-me...)
Affinity DataIC50: 1.38E+3nMAssay Description:The VHL NanoBRET Target Engagement Assay analyzes the apparent affinity of test compounds for VHL in cells by competitive displacement of a VHL NanoB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
WIPO WO2022104345