BDBM554185 (((((2R,3S,4R,5R)-5-(5-chloro-7- (cyclopentylamino)-3H-[1,2,3]triazolo[4,5- b]pyridin-3-yl)-3,4-dihydroxytetrahydrofuran-2- yl)methoxy)(methoxy)phosphoryl)methyl)phos- phonic acid::US11325938, Ex 54

SMILES COP(=O)(CP(O)(O)=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1nnc2c(NC3CCCC3)cc(Cl)nc12

InChI Key InChIKey=RGIBZIXVELCMHX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 554185   

Target5'-nucleotidase(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM554185(US11325938, Ex 54 | (((((2R,3S,4R,5R)-5-(5-chloro-...)
Affinity DataIC50: 100nMAssay Description:Assay Reaction ConditionsAssay Volume: 70 μlReaction Volume: 50 μlCD73: 0.3208 nMAMP: 15 μMAssay Buffer: 25 mM Tris-HCL, pH 7.4, 0.01%...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent