BDBM555088 US11339151, Example 64

SMILES CCN(CCN1CCC(CC1)n1ncc2cc(F)ccc12)S(=O)(=O)C(C)CO

InChI Key InChIKey=UXHXPQAQESSLQQ-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 555088   

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM555088(US11339151, Example 64)
Affinity DataKi:  1.5nMAssay Description:Human 5-HT2A Receptor, Human 5-HT7 Receptor, and Human D2 Receptor: Binding affinity of the present compound for human 5-HT2A receptor, human 5-HT7 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
US Patent

Target5-hydroxytryptamine receptor 7(Human)
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM555088(US11339151, Example 64)
Affinity DataKi:  2.40nMAssay Description:Human 5-HT2A Receptor, Human 5-HT7 Receptor, and Human D2 Receptor: Binding affinity of the present compound for human 5-HT2A receptor, human 5-HT7 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM555088(US11339151, Example 64)
Affinity DataKi:  348nMAssay Description:Human 5-HT2A Receptor, Human 5-HT7 Receptor, and Human D2 Receptor: Binding affinity of the present compound for human 5-HT2A receptor, human 5-HT7 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM555088(US11339151, Example 64)
Affinity DataIC50: 1.00E+4nMAssay Description:Extracellular and intracellular fluids used in the measurement were prepared as follows.Extracellular fluid: 2 mmol/L CaCl2, 1 mmol/L MgCl2, 10 mmol/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
US Patent