BDBM555175 US11339167, Example 36

SMILES F[C@@H]1CCN(C[C@@H]1Oc1nc(Nc2cnn(c2)C2CCNCC2)nc2[nH]ccc12)C(=O)C=C

InChI Key InChIKey=QFQRXEOQBMETNG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 555175   

TargetTyrosine-protein kinase JAK3(Human)
Daewoong Pharmaceutical

US Patent
LigandPNGBDBM555175(US11339167, Example 36)
Affinity DataIC50: 0.800nMAssay Description:Specifically, the inhibitory activities against JAK3 and BTK kinase were measured using a JAK3 kinase assay kit (Promega, V9441) and a BTK kinase ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
US Patent