BDBM555245 USRE49080, Example 11

SMILES CN1CCOc2ccc(Cc3cc(ccc3Cl)[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)cc12

InChI Key InChIKey=VDMIGDKNMBPOOL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 555245   

TargetSodium/glucose cotransporter 2(Human)
Novartis

US Patent
LigandPNGBDBM555245(USRE49080, Example 11)
Affinity DataIC50: 1.40nMAssay Description:The SGLT-2 assay is carried out as follows: CHO-hSGLT2 cells are cultivated in Ham's F12 Medium (BioWhittaker) with 10% foetal calf serum and 250...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
US Patent