BDBM555253 USRE49080, Example 24

SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(F)c(Cc2ccc3OCCNc3c2)c1

InChI Key InChIKey=DVKUSDXNSFOFKS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 555253   

TargetSodium/glucose cotransporter 2(Human)
Novartis

US Patent
LigandPNGBDBM555253(USRE49080, Example 24)
Affinity DataIC50: 1.30nMAssay Description:The SGLT-2 assay is carried out as follows: CHO-hSGLT2 cells are cultivated in Ham's F12 Medium (BioWhittaker) with 10% foetal calf serum and 250...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
US Patent

TargetSodium/glucose cotransporter 1(Human)
Novartis

US Patent
LigandPNGBDBM555253(USRE49080, Example 24)
Affinity DataIC50: 3.10E+4nMAssay Description:The SGLT-2 assay is carried out as follows: CHO-hSGLT2 cells are cultivated in Ham's F12 Medium (BioWhittaker) with 10% foetal calf serum and 250...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
US Patent