BDBM555262 USRE49080, Example 41

SMILES COc1ccc(cc1Cc1ccc2OC3(CCC3)CCc2c1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

InChI Key InChIKey=OCPUJUBLDISJNK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 555262   

TargetSodium/glucose cotransporter 2(Human)
Novartis

US Patent
LigandPNGBDBM555262(USRE49080, Example 41)
Affinity DataIC50: 16.2nMAssay Description:The SGLT-2 assay is carried out as follows: CHO-hSGLT2 cells are cultivated in Ham's F12 Medium (BioWhittaker) with 10% foetal calf serum and 250...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
US Patent

TargetSodium/glucose cotransporter 1(Human)
Novartis

US Patent
LigandPNGBDBM555262(USRE49080, Example 41)
Affinity DataIC50: 1.62E+3nMAssay Description:The SGLT-2 assay is carried out as follows: CHO-hSGLT2 cells are cultivated in Ham's F12 Medium (BioWhittaker) with 10% foetal calf serum and 250...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
US Patent