BDBM555664 5-Chloro-2-ethyl-N-(((1s,4S)-1-hydroxy-4-(methylsulfonyl)cyclohexyl)methyl)-1-((S*)-4-isobutyl-2-methoxyphenyl)-1H-imidazole-4-carboxamide::US11345666, Example 91::US11345666, Example 92

SMILES CCc1nc(C(=O)NC[C@@]2(O)CC[C@@H](CC2)S(C)(=O)=O)c(Cl)n1-c1ccc(CC(C)C)cc1OC

InChI Key InChIKey=RSEFSALSGRAGTM-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 555664   

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM555664(US11345666, Example 92 | 5-Chloro-2-ethyl-N-(((1s,...)
Affinity DataKd:  0.280nMAssay Description:ThermoFluor is a fluorescence based assay that estimates ligand binding affinities by measuring the effect of a ligand on protein thermal stability (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM555664(US11345666, Example 92 | 5-Chloro-2-ethyl-N-(((1s,...)
Affinity DataKd:  620nMAssay Description:ThermoFluor is a fluorescence based assay that estimates ligand binding affinities by measuring the effect of a ligand on protein thermal stability (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent