BDBM556649 US11352330, Example B81

SMILES Cc1cc(OCc2n[nH]c(=O)n2C)c(cc1Cl)-c1cc(CN2CCCC2=O)ccc1F

InChI Key InChIKey=JODLNNUAQCRDJB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 556649   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM556649(US11352330, Example B81)
Affinity DataIC50: 3nMAssay Description:Assay working solutions were made as follows:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent