BDBM556690 2-[[3-[(2-tert-Butyl-4-chloro-5-methylphenoxy)methyl]-1H-pyrazolo[3,4-b]pyridin-6-yl]-methylamino]ethanol::US11352330, Example D8

SMILES CN(CCO)c1ccc2c(COc3cc(C)c(Cl)cc3C(C)(C)C)n[nH]c2n1

InChI Key InChIKey=NPNNCUHJLLLTDY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 556690   

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM556690(2-[[3-[(2-tert-Butyl-4-chloro-5-methylphenoxy)meth...)
Affinity DataIC50: 6nMAssay Description:Assay working solutions were made as follows:Assay buffer (50 mM Tris-HCl, 140 mM NaCl, 5 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 0.01% Triton-X-100, pH 8.0;...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent