BDBM557109 1-(4-(2'-(4,5- Dimethyl-1H- imidazol-2-yl)- 3,4'-bipyridine- 5- carbonyl)piper- azin-1- yl)ethanone::US11352340, Example 159

SMILES CC(=O)N1CCN(CC1)C(=O)c1cncc(c1)-c1ccnc(c1)-c1nc(C)c(C)[nH]1

InChI Key InChIKey=UDDOWUQFFOKVNX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 557109   

LigandPNGBDBM557109(1-(4-(2'-(4,5- Dimethyl-1H- imidazol-2-yl)- 3,4'-b...)
Affinity DataIC50: 50nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

LigandPNGBDBM557109(1-(4-(2'-(4,5- Dimethyl-1H- imidazol-2-yl)- 3,4'-b...)
Affinity DataIC50: 100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent