BDBM557445 US11352356, Compound I-104b

SMILES CC(C)(O)c1cc(cn2cc(Cn3cc(cn3)C(=O)NCc3ncn4ccc(Cl)cc34)nc12)C1CC1

InChI Key InChIKey=BPQPMYMBGDKSGH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 557445   

TargetPlasma kallikrein(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM557445(US11352356, Compound I-104b)
Affinity DataEC50: <1nMAssay Description:Example compounds were evaluated for inhibition of the human activated kallikrein enzyme in two formats of an assay employing a fluorogenic peptide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent