BDBM557647 US11358948, Compound I-77

SMILES CC(C)(C)OC(=O)NCCOCCOCCOCCOCC#Cc1ccc(cc1)[C@H]1CN([C@H]2CCC(=O)NC2=O)C(=O)O1

InChI Key InChIKey=HMEOPGWLINAFJB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 557647   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Kymera Therapeutics

US Patent
LigandPNGBDBM557647(US11358948, Compound I-77)
Affinity DataIC50: 1.00E+3nMAssay Description:Table 2: Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2022
Entry Details
US Patent