BDBM557653 US11358948, Compound I-80

SMILES Cc1nc(c[nH]1)-c1ccc2n(C3CCC(=O)NC3=O)c(=O)n(C)c2c1

InChI Key InChIKey=BHVDYWNLSJQLID-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 557653   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Kymera Therapeutics

US Patent
LigandPNGBDBM557653(US11358948, Compound I-80)
Affinity DataIC50: 1.00E+3nMAssay Description:Table 2: Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2022
Entry Details
US Patent