BDBM557658 US11358948, Compound I-83

SMILES CC(C)(C)OC(=O)NCCOCCOCCOCCOCCCc1ccc(cc1)[C@H]1CN(C2CCC(=O)NC2=O)C(=O)O1

InChI Key InChIKey=MFQOOYBGVWKRRV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 557658   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Kymera Therapeutics

US Patent
LigandPNGBDBM557658(US11358948, Compound I-83)
Affinity DataIC50: 1.00E+3nMAssay Description:Table 2: Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2022
Entry Details
US Patent