BDBM557923 N-(2-((trans)-4-(3-chloro-5-fluoropyridin-2-yl)cyclohexyl)ethyl)tetrahydro-2H-pyran-4-amine::US11365191, Example 78

SMILES Fc1cnc([C@@H]2CC[C@H](CCNC3CCOCC3)CC2)c(Cl)c1

InChI Key InChIKey=UDJARJXZYCRFJE-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 557923   

TargetNociceptin receptor(Human)
Dart Neuroscience

US Patent
LigandPNGBDBM557923(N-(2-((trans)-4-(3-chloro-5-fluoropyridin-2-yl)cyc...)
Affinity DataIC50: 1nMAssay Description:Formula (I) compounds were tested for antagonism of the nociceptin receptor (NOP) in a cell-based cAMP assay, using the LANCE cAMP Detection Kit, Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent