BDBM558452 3-[[6-(4-Chloro-1H-pyrazol-5-yl)-3-pyridinyl]oxymethyl]-5-methylsulfonylphenol::US11365192, Example 66-1

SMILES CS(=O)(=O)c1cc(O)cc(COc2ccc(nc2)-c2[nH]ncc2Cl)c1

InChI Key InChIKey=CYJCMKSVIZOTHB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 558452   

TargetCytochrome P450 4F2(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM558452(US11365192, Example 66-1 | 3-[[6-(4-Chloro-1H-pyra...)
Affinity DataIC50: 16nMAssay Description:In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetCytochrome P450 4A11(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM558452(US11365192, Example 66-1 | 3-[[6-(4-Chloro-1H-pyra...)
Affinity DataIC50: 33nMAssay Description:In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent