BDBM558564 6-(2-chloro-3,5-dimethoxyphenyl)- N-(4-(4-methylpiperazin-1-yl) phenyl)-[1,2,4]triazolo[4',3':1,6]pyrido [2,3-d]pyridimin-2-amine::US11365196, Compound 15

SMILES COc1cc(OC)c(Cl)c(c1)-c1cc2cnc(Nc3ccc(cc3)N3CCN(C)CC3)nc2n2cnnc12

InChI Key InChIKey=KSVGDHYNBLZAIE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 558564   

TargetFibroblast growth factor receptor 1(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM558564(6-(2-chloro-3,5-dimethoxyphenyl)- N-(4-(4-methylpi...)
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of some compounds of the present disclosure against FGFR1, FGFR2, FGFR3, FGFR4, KDR was tested by mobility shift assay (conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent