BDBM558614 US11365196, Compound 106

SMILES COc1cc(OC)c(Cl)c(c1)-c1cc2cnc(Nc3ccc(cc3)N3CCN(CC3)C(C)=O)nc2n2cnnc12

InChI Key InChIKey=QGVDUZPALGLYPE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 558614   

TargetFibroblast growth factor receptor 1(Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM558614(US11365196, Compound 106)
Affinity DataIC50: 1nMAssay Description:The inhibitory activity of some compounds of the present disclosure against FGFR1, FGFR2, FGFR3, FGFR4, KDR was tested by mobility shift assay (conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent