BDBM558710 US11365204, Example 65::[1-[4-(6-oxaspiro[3.3]- heptan-2-ylamino)-5- oxido-6,7-dihydrothieno- [3,2-d]pyrimidin-5-ium-2- yl]azetidin-3-yl] isothia- zole-4-carboxylate

SMILES [O-][S+]1CCc2nc(nc(NC3CC4(COC4)C3)c12)N1CC(C1)OC(=O)c1cnsc1

InChI Key InChIKey=DFLMXCNPNVPHJO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 558710   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Union Therapeutics

US Patent
LigandPNGBDBM558710(US11365204, Example 65 | [1-[4-(6-oxaspiro[3.3]- h...)
Affinity DataIC50: 100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetTumor necrosis factor(Human)
Union Therapeutics

US Patent
LigandPNGBDBM558710(US11365204, Example 65 | [1-[4-(6-oxaspiro[3.3]- h...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent