BDBM559776 2-[6-[6-[(4-cyano-2-fluoro-phenyl)methoxy]-2-pyridyl]-6-azaspiro[2.5]octan-2-yl]-7-fluoro-3-(2-methoxyethyl)benzimidazole-5-carboxylic acid::WO2022109182, Example 7

SMILES COCCn1c(nc2c(F)cc(cc12)C(O)=O)C1CC11CCN(CC1)c1cccc(OCc2ccc(cc2F)C#N)n1

InChI Key InChIKey=NISRYFHEDSUEEQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 559776   

TargetGlucagon-like peptide 1 receptor(Human)
Gilead Sciences

WIPO
LigandPNGBDBM559776(2-[6-[6-[(4-cyano-2-fluoro-phenyl)methoxy]-2-pyrid...)
Affinity DataIC50: 3.80nMAssay Description:GLP-1R activation by a compound of the present disclosure was quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
WIPO WO2022109182

TargetGlucagon-like peptide 1 receptor(Human)
Gilead Sciences

WIPO
LigandPNGBDBM559776(2-[6-[6-[(4-cyano-2-fluoro-phenyl)methoxy]-2-pyrid...)
Affinity DataIC50: 10nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
WIPO WO2022109182