BDBM559786 Methyl (S)-2-((4-(6-((4-cyano-2-fluorobenzyl)oxy)pyridin-2-yl)piperidin-1-yl)methyl)-5-(1-methyl-1H-pyrazol-4-yl)-1-(oxetan-2-ylmethyl)-1H-benzo[d]imidazole-6-carboxylate::WO2022109182, Example 17

SMILES Cn1cc(cn1)-c1cc2nc(CN3CCC(CC3)c3cccc(OCc4ccc(cc4F)C#N)n3)n(C[C@@H]3CCO3)c2cc1C(O)=O

InChI Key InChIKey=HSAGJDNMVRMBCG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559786   

TargetGlucagon-like peptide 1 receptor(Human)
Gilead Sciences

WIPO
LigandPNGBDBM559786(Methyl (S)-2-((4-(6-((4-cyano-2-fluorobenzyl)oxy)p...)
Affinity DataIC50: 13nMAssay Description:GLP-1R activation by small molecule agonists is quantified by measuring cAMP increase in CHO cells stably expressing GLP-1R (MultiSpan product # C126...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
WIPO WO2022109182