BDBM559853 US11376258, Example 25

SMILES Clc1ccc(COC(=O)N2CCOC(C2)c2nc3cncnc3[nH]2)cc1

InChI Key InChIKey=FSPHXWITVFCTIP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 559853   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM559853(US11376258, Example 25)
Affinity DataIC50: 113nMAssay Description:At the assay day cells were washed 3× with assay buffer, 10 μL buffer remained in the wells after washing. 10 μL Ca kit loading buffer (AAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2022
Entry Details
US Patent